Ready, go! Super Elongation Complex pinpointed as a major regulator in coordinated expression of early developmental genes

Just like orchestra musicians waiting for their cue, RNA polymerase II molecules are poised at the start site of many developmentally controlled genes, waiting for the "Go!" signal to read their part of the genomic symphony. An assembly of transcription elongation factors known as Super Elongation Complex, or SEC for short, helps paused RNA polymerases to come online and start transcribing the gene ahead, researchers have now found.

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