New target found for nitric oxide's attack on salmonella bacteria

A new target for nitric oxide has been revealed in studies of how it inhibits the growth of salmonella, a bacteria that is a common cause of food poisoning. Naturally produced in the nose and gut, nitric oxide interferes at various points in the Krebs cycle, the part of cellular respiration that turns fuel into energy. Knowing how nitric oxide restricts pathogen metabolism may lead to new antimicrobials or drugs that promote the body's own natural defenses.

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