Three-part handoff delivers proteins to membrane surface

The delivery system for an important class of proteins in the cell membrane can be fully replicated with a mere three components, according to a new study. Tail-anchored proteins, the molecular machines that make up approximately five percent of the membrane proteins in a cell, are known to have their own special pathway for trafficking to the membrane after construction. New research finds that these proteins can be delivered to the membrane via a simple three-part system.

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