Orchestrator of waste removal rescues cells that can't manage their trash

Just as we must take out the trash to keep our homes clean and safe, it is essential that our cells have mechanisms for dealing with wastes and worn-out proteins. When these processes are not working properly, unwanted debris builds up in the cell and creates a toxic environment. Now, a new study describes a master regulator of the intracellular recycling and waste removal process and suggests an alternative strategy for treatment of metabolic disorders associated with the abnormal accumulation of waste in the cell.

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