Engineers use short ultrasound pulses to reach neurons through blood-brain barrier

Researchers have developed a new technique to reach neurons through the blood-brain barrier and deliver drugs safely and noninvasively. Up until now, scientists thought long ultrasound pulses, which can inflict collateral damage, were required. This new study shows that extremely short pulses of ultrasound waves can open the blood-brain barrier -- with the added advantages of safety and uniform molecular delivery -- and the molecule injected systemically could reach and highlight the targeted neurons noninvasively.

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