Study first to link mitochondrial dysfunction and alpha-Synuclein multiplication in human fibroblasts

A new study shows for the first time the effects of alpha-Synuclein gene multiplication on mitochondrial function and susceptibility to oxidative stress in human tissue. Mitochondrial dysfunction has been frequently implicated in the neurodegenerative process that underlies Parkinson's disease, but the basis for this has not been fully understood.

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