Study explains paradox of insulin resistance genetics

A paradox in understanding insulin resistance is figuring out why insulin-resistant livers make more fat. Insulin resistance occurs when the body does a poor job of lowering blood sugars. The signals to make lipid after a meal come from hormones -- most notably insulin -- and the direct effect of nutrients on the liver. Researchers describe the pathway that insulin uses to change the levels of gene expression that control lipid metabolism.

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