Colorectal cancer: Jumping gene named Sleeping Beauty plays vital role in investigating cancer pathway

A jumping gene has helped to unlock vital clues for researchers investigating the genetics of colorectal cancer. In a new study, researchers used DNA transposon system to profile the repertoire of genes that can drive colorectal cancer in a mouse model, identifying many more than previously thought. Around one third of these genes are mutated in human cancer, which provides strong evidence that they are driver mutations in human tumours.

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