Anti-sense might make sense for treating liver cancer

Tuesday, January 3, 2012 - 14:30 in Health & Medicine

A new study shows that it is possible to selectively target and block a particular microRNA that is important in liver cancer. The findings might offer a new therapy for this malignancy, which kills an estimated 549,000 people worldwide annually. The study focused on miR-221, which is consistently present at abnormally high levels in human liver cancer. The treatment significantly prolonged survival in an animal model and promoted the activity of important tumor-suppressor genes.

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