Newly identified fusion genes in lung and colorectal cancer may guide treatment with 'targeted' drugs

Tuesday, February 14, 2012 - 00:30 in Health & Medicine

Novel gene abnormalities discovered in a subpopulation of lung and colorectal tumors could potentially identify patients with a good chance of responding to highly specific “targeted” drugs already in use for treating other cancers, scientists report. The genetic alterations – pieces of two genes fused together - showed up in a massive search of the DNA in stored tumor samples of non-small cell lung cancer and colorectal cancer, said researchers. These specific genetic abnormalities had not been previously linked to the two cancer types.

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