More code cracking: Three related studies help uncover the rules governing gene transcription

A trio of groundbreaking publications report important methodological advances that will enable a better understanding of how gene expression is regulated, both in normal cells and in cancer cells. This knowledge could lead to the development of more effective therapeutic agents to treat cancer patients. The three studies focus on nucleosomes, a basic unit of DNA packaging, and may help to uncover the rules governing gene transcription.

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