Protein 'filmed' while unfolding at atomic resolution

Whether Alzheimer’s, Parkinson’s or Huntington’s Chorea – all three diseases have one thing in common: They are caused by misfolded proteins that form insoluble clumps in the brains of affected patients and, finally, destroy their nerve cells. One of the most important questions in the biological sciences and medicine is thus: How do proteins – the tools of living cells – achieve or lose their three-dimensional structure. Because only if their amino acid chains are correctly folded, can proteins perform their tasks properly.

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