Regenerating orthopedic tissues within the human body

Wednesday, February 19, 2014 - 04:32 in Biology & Nature

Performing tissue repair with stem cells typically requires applying copious amounts of growth factor proteins -- a task that is very expensive and becomes challenging once the developing material is implanted within a body. A team of biomedical engineers has developed a polymer scaffold for growing cartilage that includes gene therapy vectors to induce stem cells to produce the growth factors they need. The new technique -- biomaterial-mediated gene delivery -- is shown to produce cartilage at least as good biochemically and biomechanically as if the growth factors were introduced in the laboratory.

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