Study in fruitflies strengthens connection among protein misfolding, sleep loss, and age

Pulling an "all-nighter" before a big test is practically a rite of passage in college. Usually, it's no problem: You stay up all night, take the test, and then crash, rapidly catching up on lost sleep. But as we age, sleep patterns change, and our ability to recoup lost sleep diminishes. New research demonstrates that pathways of aging and sleep intersect at the circuitry of a cellular stress response pathway, and by tinkering with those connections, it may be possible to alter sleep patterns in the aged for the better -- at least in fruit flies.

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