Pushing cells towards a higher pluripotency state

Stem cells have the unique ability to become any type of cell. The possibility that they can be cultured and engineered in the lab makes them an attractive option for regenerative medicine. However, some conditions that are commonly used for culturing human stem cells may render the cells unusable for clinical use. These conditions cannot be avoided, however, as they help maintain the pluripotency of the stem cells. A group of researchers has gained new insight into the role of CCL2, a chemokine known to be involved in the immune response, in the enhancement of stem cell pluripotency.

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