National Xenopus resource at the MBL innovates new way to study proteins

Thursday, July 17, 2014 - 14:31 in Biology & Nature

Researchers have used mRNA sequences, rather than DNA, to more efficiently create a reference database that can be used for proteomic analysis of Xenopus frogs. The researchers used their reference database to identify over 11,000 proteins from an unfertilized Xenopus egg and estimate the abundance of these proteins. The method outperformed comparison proteomic analyses based on a preliminary, unpublished Xenopus genome and other protein reference databases.

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