Measuring the number of protein molecules inside cells

The identification of the genes and proteins involved in a biological process, as well as the way they interact, are essential for the understanding of that process. However, often little is known about the dimensions of molecular biological structures. Knowing how many molecules make up a structure and are required for its function are essential for our understanding of biological mechanisms, yet poses a difficult challenge. Now, in a breakthrough study, researchers were able to measure the amount of protein molecules in living human cells required to form the centromere.

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