Going beyond the central dogma of molecular biology: Rather than being a one-way street, DNA-directed RNA transcription may have profound adaptability

Wednesday, March 11, 2015 - 11:52 in Biology & Nature

The central dogma of molecular biology describes the flow of genetic information. It was first described by Francis Crick in 1956 as one-way traffic: as: "DNA makes RNA and RNA makes protein." A recent paper, however, suggests that rather than being a one-way street, DNA-directed RNA transcription may have profound adaptability. The authors of the paper showed a conceptually novel relationship between the genotype (DNA) and the phenotype (the products of the transcription of DNA).

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