First signalling pathway of the digestive lineage in planarians better understood

Friday, May 20, 2016 - 12:01 in Biology & Nature

A scientific study describes for the first time the function of a signalling pathway –particularly, the pathway of epidermal growth factor receptors (EGFR) - in the differentiation of the planarian digestive lineage. EGFR pathway, evolutionarily preserved, has a fundamental role when regulating the cell differentiation and proliferation in lots of organisms (such as mammals’ neural stem cells) and it is over-activated in most of human cancers.

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