Pathogen: Temperature influences gene expression, life cycle in vibrio cholerae

Saturday, May 21, 2016 - 11:10 in Biology & Nature

Vibrio cholerae infects roughly four million people annually, worldwide, causing severe diarrheal disease, and killing an estimated 140,000 people. Its success as a pathogen belies the challenges this bacterium faces. The waters this bacterium inhabits when it's not infecting H. sapiens can be 40 degrees Fahrenheit cooler than our normal body temperature. Now a team of investigators provides new insights into how different temperatures in the bacterium's environment control expression of genes required for life at those temperatures.

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