Excess Serotonin Receptors Undercut Effectiveness Of Antidepressants

Thursday, January 14, 2010 - 14:00 in Health & Medicine

An excess of a particular serotonin receptor in the center of the brain may explain why antidepressants fail to relieve depression symptoms for 50 percent of patients, indicates a new study published in Neuron. The authors say the study is the first to find a causal link between receptor number and antidepressant treatment and may lead to more personalized treatment for depression, including treatments for patients who do not respond to antidepressants and ways to identify these patients before they undergo costly, and ultimately, futile therapies. read more

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