World's Smallest Reaction Chamber - A Tiny Spray Of Fluid

Friday, December 7, 2012 - 04:10 in Physics & Chemistry

The world's smallest reaction chamber has a mixing volume that can be measured in femtoliters - that's a million billionths of a liter. The reaction chamber actually consists of nothing more than a tiny spray of liquid, produced by a technique known as electrospray ionization, in which a liquid is converted into lots of charged droplets by exposing it to a high voltage as it exits the nozzle of a thin capillary. Like water being sprayed out of a hose, these charged droplets form a cone shape, known as a Taylor cone, as they are emitted from the nozzle. Because the electrospray process transforms any chemical entities within the liquid into ions, it is a commonly used technique for ionizing a liquid sample prior to analysis by mass spectrometry. read more

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