The Molecular High-Speed Origami Of Protein Folding

Proteins, those workhorses of the cell responsible for almost all biological functions, have to be adaptable and that means chain-like molecules must engage in an intricate three-dimensional conformation. This process - protein folding - is one of the most important in biology. In the event of improper folding, proteins can't perform their duties and may even lump together in aggregates, which can lead to severe diseases like Alzheimer's or Parkinson's. To prevent that, specialized proteins, so-called chaperones, help other proteins to adopt their proper shape.  read more

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