The Key To Vitamin A Metabolism Is Lecithin Retinol Acyltransferase
Wednesday, December 10, 2014 - 14:01
in Health & Medicine
The discovery of the mechanism that enables the enzyme Lecithin: retinol acyltransferase (LRAT) to store vitamin A, a process that is indispensable for vision, may provide a boost for designing small molecule therapies for degenerative eye diseases. The same enzymatic activity of LRAT that allows specific cells to absorb vitamin A can be used to transport small molecule drugs to the eye. These drugs would accumulate in eye tissue, lowering the effective dose and reducing risk of systemic side effects. read more