May repairs full of mistakes develop into cancer?
Tuesday, May 24, 2016 - 17:20
in Biology & Nature
These are DNA double-strand breaks, introduced by ionizing radiation or other mechanisms, are repaired rapidly and precisely in normal cells (right pathway). In contrast, compromised Tel1 activation with inefficient end... A group of researchers at Osaka University found that if DNA damage response (DDR) does not work when DNA is damaged by radiation, proteins which should be removed remain instead, and a loss of genetic information can be incited, which, when repaired incorrectly, will lead to the tumor formation.