Editing Immune Response Could Make Gene Therapy More Effective

Friday, September 4, 2020 - 10:41 in Biology & Nature

Gene therapy generally relies on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In case of CRISPR-based gene therapies, molecular scissors can then snip out a defective gene, add in a missing sequence or enact a temporary change in its expression, but the body’s immune response to AAV can thwart the […]

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