Targeting By Degradation: A New Way Forward For Treating Leukemias?

Tuesday, December 16, 2008 - 23:21 in Health & Medicine

Used with success for treating acute promyelocytic leukemias, retinoic acid and arsenic oxide induce the differentiation of malignant cells. Is this differentiation responsible for the eradication of the disease? Researchers have managed to prove that this is not the case: the remissions are above all linked to the disappearance of the malignant stem cells responsible for the leukemia.

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