See-through 'MitoFish' opens a new window on brain diseases

Wednesday, December 5, 2012 - 11:01 in Biology & Nature

Scientists have demonstrated a new model for investigating mechanisms at work in Alzheimer's and other neurodegenerative diseases, which also could prove useful in the search for effective drugs. They turned to the zebrafish, transparent in its embryonic stages, and developed a transgenic variety called the "MitoFish." This new model enables them to see – within individual neurons of living animals – how brain diseases disturb the transport of mitochondria, the power plants of the cell.

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