Newly described type of immune cell and T cells share similar path to maturity
Tuesday, May 14, 2013 - 20:30
in Biology & Nature
Innate lymphoid cells protect boundary tissues such as the skin, lung, and the gut from microbial onslaught. They also have shown they play a role in inflammatory disease. Researchers have found that maturation of ILC2s requires T-cell factor 1 to move forward. They describe that one mechanism used to build ILCs is the same as that in T cells. Both cell types use a protein pathway centered on Notch.