Two forms of Parkinson's disease identified

Saturday, October 12, 2013 - 10:00 in Biology & Nature

Why can the symptoms of Parkinson’s disease vary so greatly from one patient to another? A consortium of researchers is well on the way to providing an explanation. Parkinson’s disease is caused by a protein known as alpha-synuclein, which forms aggregates within neurons, killing them eventually. The researchers have succeeded in characterizing and producing two different types of alpha-synuclein aggregates. Better still, they have shown that one of these two forms is much more toxic than the other and has a greater capacity to invade neurons.

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