SIRT5 regulation has dramatic effect on mitochondrial metabolism

Wednesday, December 11, 2013 - 10:31 in Health & Medicine

The Sirtuin family of protein deacylases has received considerable attention due to its links to longevity, diabetes, cancer, and metabolic regulation. Researchers identified widespread regulation of proteins involved in metabolism by the mitochondrial sirtuin, SIRT5. These and related findings have widespread implications for understanding metabolic function in both normal and disease states.

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