Cortical convolutions controlled in sections: Non-coding DNA sequence affects brain's characteristic folding, study shows

Friday, February 14, 2014 - 14:31 in Biology & Nature

Researchers have tied a particular gene to the development of cortical convolutions -- the prominent but enigmatic folds covering the surface of the human brain. Their discovery should shed some light on these characteristic contours, which have been the subject of wild speculation for ages, and perhaps also provide a better understanding of how such brain ridges form, how they evolved from our pre-human ancestors and, ultimately, how they influence brain function.

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