Mechanism of cancer caused by loss of BRCA1, BRCA2 gene function identified
Monday, April 28, 2014 - 18:01
in Health & Medicine
Inherited mutations in the BRCA1 or BRCA2 tumor suppressor genes are by far the most frequent contributors of hereditary cancer risk in the human population, often causing breast or ovarian cancer in young women of child-bearing age. Now investigators report a new mechanism by which BRCA gene loss may accelerate cancer-promoting chromosome rearrangements.