ACE-inhibitors associated with lower risk for ALS above certain dose over time

Wednesday, November 12, 2014 - 04:31 in Health & Medicine

ALS is a progressive neurodegenerative disease and most patients die within three to five years after symptoms appear. Studies have suggested antihypertensive medications angiotensin-converting enzyme inhibitors (ACEIs) may decrease the risk for developing neurodegenerative diseases. "The findings in this total population-based case-control study revealed that long-term exposure to ACEIs was inversely associated with the risk for developing ALS. To our knowledge, the present study is the first to screen the association between ACEIs and ALS risk in a population-based study," note the authors.

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