New DNA 'shredder' technique goes beyond CRISPR's scissors
Monday, April 8, 2019 - 18:30
in Biology & Nature
An international team has unveiled a new CRISPR-based tool that acts more like a shredder than the usual scissor-like action of CRISPR-Cas9. The new approach, based on Type I CRISPR-Cas3, is able to wipe out long stretches of DNA in human cells with programmable targeting, and has been shown to work in human cells for the first time.