Why Don't Antidepressants Act Faster?

Sunday, September 15, 2013 - 10:50 in Health & Medicine

It often takes several weeks to feel the effect of newly prescribed antidepressants - a lingering mystery and a frustration to both patients and physicians. CREB, and CREM to some degree, has been implicated in the pathophysiology of depression, as well as in the efficacy of antidepressants. However, whenever CREB is deleted, CREM is upregulated, further complicating the story. read more

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