Cloud computing method greatly increases gene analysis

Wednesday, September 8, 2010 - 22:07 in Mathematics & Economics

Researchers at the Johns Hopkins Bloomberg School of Public Health have developed new software that greatly improves the speed at which scientists can analyze RNA sequencing data. RNA sequencing is used to compare differences in gene expression to identify those genes that switched on or off when, for instance, a particular disease is present. However, sequencing instruments can produce billions of sequences per day, which can be time-consuming and costly to analyze. The software, known as Myrna, uses "cloud computing," an Internet-based method of sharing computer resources. Faster, cost-effective analysis of gene expression could be a valuable tool in understanding the genetic causes of disease. The findings are published in the current edition of the journal Genome Biology. The Myrna software is available for free download at http://bowtie-bio.sf.net/myrna.

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