Researchers demonstrate that messenger RNA are lost in translation

Case Western Reserve University School of Medicine assistant professor in the Center for RNA Molecular Biology, Jeff Coller, Ph.D., and his team discovered that messenger RNA (mRNA) predominately degrade on ribosomes, fundamentally altering a common understanding of how gene expression is controlled within the cell. The study, "Co-translational mRNA decay in Saccharomyces cerevisiae", is published in the latest issue of Nature.

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