Master gene SRC-3 enables breast cancer growth, invasion

The master gene called SRC-3 (steroid receptor coactivator 3) not only enhances estrogen-dependent growth of cancer cells by activating and encouraging the transcription of a genetic message into a protein, it also sends a signal to the cell membrane to promote cell motility or movement - a key element of cancer spread or metastasis, said Baylor College of Medicine researchers and collaborators in a report that appears in the current issue of the journal Molecular Cell.

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