Master gene SRC-3 enables breast cancer growth, invasion

The master gene SRC-3 not only enhances estrogen-dependent growth of cancer cells, it also sends a signal to the cell membrane to promote cell movement -- a key element of cancer metastasis, said researchers. The finding not only uncovers a new activity for SRC-3, it also clears up a mystery about how the message that tells a cell to invade gets from the epidermal growth factor receptor to the activating enzyme.

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