Researchers identify a new breast and ovarian cancer susceptibility gene

A group of researchers report evidence unambiguously implicating the gene RAD51C in susceptibility to breast and ovarian cancer. This gene normally plays a role in DNA repair. By screening RAD51C in unrelated individuals from 1,100 German families with hereditary breast and ovarian cancers, the researchers identified six mutations that increase cancer risk. Their findings are published in Nature Genetics.

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