New genetic analysis reveals principles of phenotypic expression

Tuesday, June 22, 2010 - 12:31 in Biology & Nature

The Human Genome Project, along with numerous parallel efforts to solve the DNA sequences of hundreds of animal, plant, fungal, and microbe genomes in the last few decades, has produced enormous amounts of genetic data with which researchers are struggling to keep pace. Knowing gene sequences, after all, may not directly reveal what roles that genes play in the actual manifestation of physical traits (or phenotypes) of an organism -- including their roles in human diseases. To help navigate the new genomic landscape, researchers are developing experimental approaches and analysis tools to help prioritize and organize complex genetic information with respect to phenotypic effects.

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