A fateful pause: Genetic mechanism once thought rare may allow rapid cell production

Thursday, July 8, 2010 - 12:21 in Health & Medicine

We take our blood for granted, but its creation requires a complicated series of steps, starting with the formation of blood stem cells during early embryonic development, followed by progressive differentiation into the progenitors of red cells, white cells and platelets, and ultimately the full set of blood cells. Now, in the July 9 issue of Cell, researchers at Children's Hospital Boston report a surprising twist in how mature red blood cells form - which may explain the body's ability to rapidly replenish them in response to injury.

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