CD74 serves as a survival receptor on colon epithelial cells

CD74 is a protein expressed by cells of the immune system. A research group in Israel finds that CD74 is expressed on colon epithelial cells of mice, as well as on a malignant cell line from mouse colon. Stimulation of CD74 leads to a signaling cascade resulting in cell survival. Thus, CD74 is a survival receptor in health and disease.

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