Interfering with a double-edged sword: Novel anti-inflammatory functions for interferons

One of the body's first protective reactions to infection is inflammation, typically stimulated by the factor IL-1beta. Unfortunately, inflammation frequently occurs when it is not desired and so must be treated, e.g. by blocking IL-1beta production or activity. The picture is complicated by the fact that many other factors are involved in the process. A precise understanding of the regulatory networks is important for the development of anti-inflammatory treatments.

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