Studies provide new insights into the genetics of obesity and fat distribution

An international consortium has made significant inroads into uncovering the genetic basis of obesity by identifying 18 new gene sites associated with overall obesity and 13 that affect fat distribution. The studies include data from nearly a quarter of a million participants, the largest genetic investigation of human traits to date. The papers, both from the GIANT (Genetic Investigation of ANthropometric Traits) consortium – which consists of more than 400 scientists from 280 research institutions worldwide – will appear in Nature Genetics and are receiving early online publication.

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