Trigger mechanism provides 'quality control' in cell division

Monday, November 22, 2010 - 12:03 in Biology & Nature

Researchers from Huntsman Cancer Institute (HCI) at the University of Utah report that they have identified a previously undiscovered trigger mechanism for a quality control checkpoint at the very end of the cell division process in a paper to be published in the November 29 issue of The Journal of Cell Biology and online today. This trigger mechanism monitors whether the cell's nucleus, where the DNA resides, has the proper structure and delays cell division if the structure is not correct. Previously discovered triggers have been associated with improper DNA division and distribution, but not the nuclear structure.

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