Researchers demonstrate continuous and controlled translocation of DNA polymer through a nanopore

Research published this week in JACS (Journal of the American Chemical Society) shows continuous and controlled translocation of a single stranded DNA (ssDNA) polymer through a protein nanopore by a DNA polymerase enzyme. The paper by researchers at the University of California Santa Cruz (UCSC) provides the foundation for a molecular motor, an essential component of Strand Sequencing using nanopores. Researchers at UCSC are collaborating with the UK-based company Oxford Nanopore Technologies, developers of a nanopore DNA sequencing technology.

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