Firefly glow: Scientists develop a safe hydrogen peroxide probe based on firefly luciferin

Friday, February 11, 2011 - 07:00 in Biology & Nature

(PhysOrg.com) -- A unique new probe based on luciferase, the enzyme that gives fireflies their glow, enables researchers to monitor  hydrogen peroxide levels in mice and thereby track the progression of infectious diseases or cancerous tumors without harming the animals or even having to shave their fur. Developed by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley, this new bioluminescent probe has already provided the first direct experimental evidence that hydrogen peroxide is continuously made even in a healthy animal.

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