Researchers have found how brain cells control their movement to form the cerebral cortex

A study led by Academy Research Fellow Eleanor Coffey identifies new players that put the brakes on. They show in mice that lack the star player "JNK1", that newborn neurons spend less time in the multipolar stage, which is when the cells prepare for subsequent expedition, possibly choosing the route to be taken. Having hurried through this stage, they move off at high speed to reach their final destinations in the cortex days earlier and less precisely than in a normal mouse. The results of their study are published in the latest issue of Nature Neuroscience.

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